SARS-CoV-2-IN-108

SARS-CoV-2-IN-108

• UNSPSC Description: SARS-CoV-2-IN-108 (Compound 29) is an inhibitor for SARSCoV-2 papain-like protease with an IC50 of 0.14 µM. SARS-CoV-2-IN-108 inhibits the virus replication with an EC50 of 0.21 µM[1].
• Target Antigen: SARS-CoV; Virus Protease
• Type: Reference compound
• Related Pathways: Anti-infection
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/sars-cov-2-in-108.html
• Smiles: CCOC(/C=C/C(NNC(CCC1=C(C(N[C@H](C)C2=CC=CC(C3=CC=CS3)=C2)=O)C=CC=C1)=O)=O)=O
• Molecular Weight: 519.61
• References & Citations: [1]Rouch CC, et al., Synthesis and Structure-Activity Relationship of Covalent Inhibitors of SARS-CoV-2 Papain-Like Protease with Antiviral Potency. Bioorg Med Chem Lett. 2025 Feb 1;116:130034.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported