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Anticancer agent 158

CAT: 0804-HY-156097Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-156097Size:1 Each
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Description
Anticancer agent 158 (compound 7c) is a potent anticancer agent. The IC50s for inhibiting HepG-2, MDA-MB-231, and HCT-116 cell lines are 7.93 μM, 9.28 μM, 13.28 μM, and 181.89 μM, respectively[1].
CAS Number
[2978685-72-0]
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-158.html
Solubility
10 mM in DMSO
Smiles
CC1=C(/C(C)=N/NC2=NC(C)=C(/N=N/C3=CC=C(OC)C=C3)S2)SC(N/N=C(C4=CNC5=C4C=CC=C5)\C)=N1
Molecular Formula
C27H27N9OS2
Molecular Weight
557.69
References & Citations
[1]Al-Humaidi J Y, et al. Synthesis, Biological Evaluation, and Molecular Docking of Novel Azolylhydrazonothiazoles as Potential Anticancer Agents[J]. ACS Omega, 2023.. . .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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