Anticancer agent 158

• UNSPSC Description:

  Anticancer agent 158 (compound 7c) is a potent anticancer agent. The IC50s for inhibiting HepG-2, MDA-MB-231, and HCT-116 cell lines are 7.93 μM, 9.28 μM, 13.28 μM, and 181.89 μM, respectively[1].

• Target Antigen:

  EGFR

• Type:

  Reference compound

• Related Pathways:

  JAK/STAT Signaling;Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-programmed cell death

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/anticancer-agent-158.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=C(/C(C)=N/NC2=NC(C)=C(/N=N/C3=CC=C(OC)C=C3)S2)SC(N/N=C(C4=CNC5=C4C=CC=C5)\C)=N1

• Molecular Weight:

  557.69

• References & Citations:

  [1]Al-Humaidi J Y, et al. Synthesis, Biological Evaluation, and Molecular Docking of Novel Azolylhydrazonothiazoles as Potential Anticancer Agents[J]. ACS Omega, 2023.. . .

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4