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Anti-inflammatory agent 52

CAT: 0804-HY-155780Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-155780Size:1 Each
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Description
Anti-inflammatory agent 52 (compound 7j) is an orally active selective COX-2 inhibitor. Anti-inflammatory agent 52 has anti-HT29 transfer activity, which leads to periodic arrest in G2/M phase. Anti-inflammatory agent 52 has safety, moderate ability to suppress inflammation. Anti-inflammatory agent 52 has a rare property of suppressing the development of tumor in mouse model, showing anti-cancer activity[1].
CAS Number
9007-83-4
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-inflammatory-agent-52.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(Cl)C=C1)COC2=CC=C(N3C(C4=CC=C(C)C=C4)SCC3=O)C=C2
Molecular Formula
C24H21ClN2O3S
Molecular Weight
452.95
References & Citations
[1]Shawky AM, et al. Discovery and optimization of 2,3-diaryl-1,3-thiazolidin-4-one-based derivatives as potent and selective cytotoxic agents with anti-inflammatory activity. Eur J Med Chem. 2023 Nov 5;259:115712.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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