17β-HSD10-IN-3

• UNSPSC Description:

  17β-HSD10-IN-3 (compound 23) is a 17β-HSD10 inhibitor with the IC50 of 5.59 μM. 17β-HSD10-IN-3 shows no cell cytotoxicity toward the HEK-293 cell line up to 20 μM[1].

• Target Antigen:

  Endogenous Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/17β-hsd10-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)OC(CCCCC(O)=O)=O)([H])[C@@]4([H])[C@](CC3)(CCC4)C

• Molecular Weight:

  402.57

• References & Citations:

  [1]Michaela Hanzlova, et al. C-3 Steroidal Hemiesters as Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 10. ACS Omega 2024.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2225109-18-0