Products for Research Use Only

Antibacterial agent 166

CAT: 0804-HY-155491Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-155491Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Antibacterial agent 166 (Compound 19q), a derivative of Nitisinone , is a selective and orally active Fusobacterium nucleatum inhibitor with a MIC50 of 1 μg/mL. Antibacterial agent 166 effectively attenuates the migratory ability of MC-38 cells induced by Fusobacterium nucleatum. Antibacterial agent 166 is a promising anti-F. nucleatum lead compound and can be used for colorectal cancer (CRC) research[1].
CAS Number
9007-83-4
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-166.html
Solubility
10 mM in DMSO
Smiles
ClC1=CN=C(CNC(C2=CC=C([N+]([O-])=O)O2)=O)C=C1
Molecular Formula
C11H8ClN3O4
Molecular Weight
281.65
References & Citations
[1]Pan Z, et al. Discovery of New Fusobacterium nucleatum Inhibitors to Attenuate Migratory Capability of Colon Cancer Cells by the Drug Repositioning Strategy. Journal of Medicinal Chemistry. 2023 Nov 20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Popular Products