NEt-iFQ

NEt-iFQ

• CAS Number: 1251538-60-9
• UNSPSC Description: NEt-iFQ is a fluorescent retinoid X receptor (RXR) agonist with potent solvatochromic properties. NEt-iFQ selectively binds to RXR-LBP and fluoresces[1].
• Target Antigen: RAR/RXR
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/net-ifq.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C=C(C(F)(F)F)C2=C(C=C(N(CC)C3=CC=C(C(O)=O)C=N3)C=C2)N1CC(C)C
• Molecular Weight: 433.42
• References & Citations: [1]Miura K, et al. Direct evaluation of polarity of the ligand binding pocket in retinoid X receptor using a fluorescent solvatochromic agonist. Bioorg Med Chem Lett. 2023 Nov 15;96:129536.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported