NEt-iFQ

• CAS Number:

  1251538-60-9

• UNSPSC Description:

  NEt-iFQ is a fluorescent retinoid X receptor (RXR) agonist with potent solvatochromic properties. NEt-iFQ selectively binds to RXR-LBP and fluoresces[1].

• Target Antigen:

  RAR/RXR

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/net-ifq.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C=C(C(F)(F)F)C2=C(C=C(N(CC)C3=CC=C(C(O)=O)C=N3)C=C2)N1CC(C)C

• Molecular Weight:

  433.42

• References & Citations:

  [1]Miura K, et al. Direct evaluation of polarity of the ligand binding pocket in retinoid X receptor using a fluorescent solvatochromic agonist. Bioorg Med Chem Lett. 2023 Nov 15;96:129536.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported