β-NETA

• Description :

  β-NETA is a potent and noncompetitive choline acetyltransferase (ChA; IC50=76 μM) and cholinesterase (ChE; IC50=40 μM) inhibitor. β-NETA weakly inhibits acetylcholinesterase (AChE; IC50=1 mM) [1][2].

• UNSPSC :

  12352005

• Target :

  Apoptosis; Cholinesterase (ChE)

• Type :

  Reference compound

• Related Pathways :

  Apoptosis; Neuronal Signaling

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/beta-neta.html

• Purity :

  98.0

• Solubility :

  DMSO : 31.25 mg/mL (ultrasonic)

• Smiles :

  O=C(C1=CC=C2C=CC=CC2=C1)CC[N+](C)(C)C.[I-]

• Molecular Formula :

  C16H20INO

• Molecular Weight :

  369.24

• References & Citations :

  [1]Sastry BV, et al. Relationships between chemical structure and inhibition of choline acetyltransferase by 2- (alpha-naphthoyl) ethyltrimethylammonium and related compounds. Pharmacol Res Commun. 1988 Sep;20 (9) :751-71.|[2]B V Sastry, et al. 2- (alpha-Naphthoyl) ethyltrimethylammonium iodide and its beta-isomer: new selective, stable and fluorescent inhibitors of choline acetyltransferase. J Pharmacol Exp Ther. 1988 Apr;245 (1) :72-80.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  AChE

• CAS Number :

  [31059-54-8]