β-NETA

CAT: 0804-HY-124957-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-124957-01Size:5 mg
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Description
β-NETA is a potent and noncompetitive choline acetyltransferase (ChA; IC50=76 μM) and cholinesterase (ChE; IC50=40 μM) inhibitor. β-NETA weakly inhibits acetylcholinesterase (AChE; IC50=1 mM) [1][2].
CAS Number
[31059-54-8]
UNSPSC
12352005
Target
Apoptosis; Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Apoptosis; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/beta-neta.html
Purity
98.0
Solubility
DMSO : 31.25 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C2C=CC=CC2=C1)CC[N+](C)(C)C.[I-]
Molecular Formula
C16H20INO
Molecular Weight
369.24
References & Citations
[1]Sastry BV, et al. Relationships between chemical structure and inhibition of choline acetyltransferase by 2- (alpha-naphthoyl) ethyltrimethylammonium and related compounds. Pharmacol Res Commun. 1988 Sep;20 (9) :751-71.|[2]B V Sastry, et al. 2- (alpha-Naphthoyl) ethyltrimethylammonium iodide and its beta-isomer: new selective, stable and fluorescent inhibitors of choline acetyltransferase. J Pharmacol Exp Ther. 1988 Apr;245 (1) :72-80.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE

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