Cavα2δ1&NET-IN-3

Cavα2δ1&NET-IN-3

• CAS Number: 2143584-82-9
• UNSPSC Description: Cavα2δ1&NET-IN-3 (example 216) is an inhibitor of the subunit α2δ of voltage-gated calcium channels (VGCC) and noradrenaline transporter (NET). Cavα2δ1&NET-IN-3 has Kis of 100-500 nM for human α2δ-1 subunit of Cav2.2 calcium channel and NET, respectively[1].
• Target Antigen: Calcium Channel
• Type: Reference compound
• Related Pathways: Membrane Transporter/Ion Channel;Neuronal Signaling
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Endocrinology; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/cavα2δ1-net-in-3.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C2=CN=C(NCC)N=C2N(CCN1C3=CC(O[C@H](C4=CC=CS4)CCNC)=CC=C3)C
• Molecular Weight: 466.60
• References & Citations: [1]Félix CUEVAS-CORDOBÉS, et al. Tetrahydropyrimidodiazepine and tetrahydropyridodiazepine compounds for treating pain and pain related conditions. WO2017191304A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported