SP-2-225

CAT: 0804-HY-155176Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-155176Size:1 Each
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Description
SP-2-225 is a selective HDAC6 inhibitor. SP-2-225 enhance the production of cancer-associated antigens and macrophage antigen cross-presentation to T cells. SP-2-225 reduces the tumor volume in a syngeneic SM1 melanoma model[1].
CAS Number
[2364448-93-9]
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sp-2-225.html
Solubility
10 mM in DMSO
Smiles
CC1=C(COC2=CC=C(CNCCCCCC(NO)=O)C=C2C)C=CC=C1C3=CC=CC=C3
Molecular Formula
C28H34N2O3
Molecular Weight
446.58
References & Citations
[1]Scott Grindrod, et al. Abstract PO023: Immune-mediated tumor growth inhibition by selective HDAC6 inhibitor SP-2-225. Cancer Immunol Res (2021) 9 (2_Supplement) : PO023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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