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MCI-225 (dehydratase)

CAT: 0804-HY-123498Size: 1 EachDry Ice: NoHazardous: No
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Description
MCI-225 dehydratase is an orally active and selective noradrenaline reuptake inhibitor. MCI-225 dehydratase also is a 5-HT3 antagonist and shows antidepressant effects in vivo[1].
CAS Number
99487-26-0
Product Name Alternative
DDP 225 (dehydratase)
UNSPSC
12352005
Target
5-HT Receptor; Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mci-225-dehydratase.html
Solubility
10 mM in DMSO
Smiles
CC1=CC2=C(C3=CC=CC=C3F)N=C(N4CCNCC4)N=C2S1.Cl
Molecular Formula
C17H18ClFN4S
Molecular Weight
364.87
References & Citations
[1]Eguchi J, et al. The anxiolytic-like effect of MCI-225, a selective NA reuptake inhibitor with 5-HT3 receptor antagonism[J]. Pharmacology Biochemistry and Behavior, 2001, 68 (4) : 677-683.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

Thieno(2,3-d)pyrimidine, 4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl)-, monohydrochloride
CAS Number99487-26-0
PubChem CID3062912
IUPAC Name4-(2-fluorophenyl)-6-methyl-2-piperazin-1-ylthieno[2,3-d]pyrimidine;hydrochloride
Molecular FormulaC17H18ClFN4S
Molecular Weight364.9
Topological Polar Surface Area69.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Heavy Atom Count24
Formal Charge0
Complexity406
SMILES
CC1=CC2=C(N=C(N=C2S1)N3CCNCC3)C4=CC=CC=C4F.Cl
InChI
InChI=1S/C17H17FN4S.ClH/c1-11-10-13-15(12-4-2-3-5-14(12)18)20-17(21-16(13)23-11)22-8-6-19-7-9-22;/h2-5,10,19H,6-9H2,1H3;1H
InChIKey
ULXKGHLJAPRUPC-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Thieno(2,3-d)pyrimidine, 4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl)-, monohydrochloride
CAS: 99487-26-0
CID: 3062912
Formula: C17H18ClFN4S
MW: 364.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight364.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Exact Mass364.0924736
Monoisotopic Mass364.0924736
Topological Polar Surface Area69.3 Ų
Heavy Atom Count24
Formal Charge0
Complexity406
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
GTR19234173-01MCI-225 dehydratase
KFA99148-01MCI 225
M21940-01MCI-225
A15502-100MCI-225 100mg
A15502-50MCI-225 50mg
A15502-1MCI-225 1mg
A15502-200MCI-225 200mg
A15502-10MCI-225 10mg
A15502-25MCI-225 25mg
A15502-5MCI-225 5mg

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