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Antiproliferative agent-32

CAT: 0804-HY-155124Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-155124Size:1 Each
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Description
Antiproliferative agent-32 (Compound 1c) inhibits the phosphorylation of PI3K/Akt/mTOR signaling pathway. Antiproliferative agent-32 inhibits Huh7 and SK-Hep-1 cells proliferation, and induce cells apoptosis, causes mitochondrial damage. Antiproliferative agent-32 can be used for research of hepatocellular carcinoma[1].
CAS Number
2925814-05-5
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antiproliferative-agent-32.html
Solubility
10 mM in DMSO
Smiles
CC(OC1=CC=CC=C1/C=C/C2=NC=CC3=CC=CC=C23)=O
Molecular Formula
C19H15NO2
Molecular Weight
289.33
References & Citations
[1]Wang Y, et al. Design, synthesis, and biological evaluation of 1-styrenyl isoquinoline derivatives for anti-hepatocellular carcinoma activity and effect on mitochondria. Eur J Med Chem. 2023 Aug 5;256:115420.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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