Antiproliferative agent-10

CAT: 0804-HY-150966Size: 1 EachDry Ice: NoHazardous: No

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Description

Antiproliferative agent-10 (compound 8) is an anti-tumour ruthenium (II) -tris-pyrazolylmethane complex that inhibits the growth of cancer cells by inhibiting mitochondrial calcium uptake[1].

CAS Number

9007-83-4

UNSPSC

12352005

Target

Mitochondrial Metabolism

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/antiproliferative-agent-10.html

Solubility

10 mM in DMSO

Smiles

[H]c12n3cccn3[Ru+](n4n2ccc4)(Cl)([P](C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)(C#[N]C8CCCCC8)n9n1ccc9.[Cl-]

Molecular Formula

C35H36Cl2N7PRu

Molecular Weight

757.66

References & Citations

[1]Jakub Cervinka, et al. Ruthenium (II) -Tris-pyrazolylmethane Complexes Inhibit Cancer Cell Growth by Disrupting Mitochondrial Calcium Homeostasis. J Med Chem. 2022 Aug 1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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