Antihypertensive agent 3

• UNSPSC Description:

  Antihypertensive agent 3 (compound 4a) is an antagonis of angiotensin II receptor 1. Antihypertensive agent 3 exhibits antihypertensive activity in a spontaneously hypertensive rats (SHRs) model[1].

• Target Antigen:

  Angiotensin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/antihypertensive-agent-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(O)C1=C(C2=CC=CC=C2)N(S(C)(=O)=O)C3=CC=CC=C31

• Molecular Weight:

  315.34

• References & Citations:

  [1]Danilenko AV, et al. Design, synthesis and biological evaluation of novel indole-3-carboxylic acid derivatives with antihypertensive activity. Bioorg Med Chem Lett. 2023 Jun 15;90:129349.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4