PHA-690509

• Description :

  PHA-690509 is an anti-ZikV compound that inhibits ZikV replication. PHA-690509 is also a CDK inhibitor, and inhibits caspase-3 activity[1][2].

• UNSPSC :

  12352005

• Target :

  Caspase; CDK; Flavivirus

• Type :

  Reference compound

• Related Pathways :

  Anti-infection; Apoptosis; Cell Cycle/DNA Damage

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/pha-690509.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C[C@@H](C1=CC=C(NC(C)=O)C=C1)C(NC2=NC=C(C(C)C)S2)=O

• Molecular Formula :

  C17H21N3O2S

• Molecular Weight :

  331.43

• References & Citations :

  [1]Devillers J. Repurposing drugs for use against Zika virus infection. SAR QSAR Environ Res. 2018 Feb;29 (2) :103-115.|[2]Alam A, et al. Recent trends in ZikV research: A step away from cure. Biomed Pharmacother. 2017 Jul;91:1152-1159.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [492445-28-0]