PHA-782584

• Description :

  PHA-782584 is a metabolite of sunitinib. Sunitinib is an oral multitargeted tyrosine kinase inhibitor with antitumor activities[1].

• UNSPSC :

  12352005

• Target :

  Drug Metabolite

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/pha-782584.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(NCCN(CC)CC)C1=C(NC(/C=C2C(NC3=C\2C=C(C=C3)O)=O)=C1C)C

• Molecular Formula :

  C22H28N4O3

• Molecular Weight :

  396.48

• References & Citations :

  [1]Speed B, et al. Pharmacokinetics, distribution, and metabolism of [14C]sunitinib in rats, monkeys, and humans. Drug Metab Dispos. 2012 Mar;40 (3) :539-55.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1126899-61-3]