2’,3’,5’-Tri-O-acetyl-5,N3-dimethyluridine

• UNSPSC Description:

  2’,3’,5’-Tri-O-acetyl-5,N3-dimethyluridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Oligonucleotides

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/2-3-5-tri-o-acetyl-5-n3-dimethyluridine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N(C)C(C(C)=C1)=O)N1[C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H]2OC(C)=O

• Molecular Weight:

  398.36

• References & Citations:

  [1]Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  201421-00-3