2’,3’,5’-Tri-O-acetyl-5-methoxycarbonylmethyl-2-thiouridine

2’,3’,5’-Tri-O-acetyl-5-methoxycarbonylmethyl-2-thiouridine

• CAS Number: 1613530-52-1
• UNSPSC Description: 2’,3’,5’-Tri-O-acetyl-5-methoxycarbonylmethyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/2-3-5-tri-o-acetyl-5-methoxycarbonylmethyl-2-thiouridine.html
• Solubility: 10 mM in DMSO
• Smiles: CC(O[C@H]1[C@@H](OC(C)=O)[C@H](N2C(NC(C(CC(OC)=O)=C2)=O)=S)O[C@@H]1COC(C)=O)=O
• Molecular Weight: 458.44
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported