2’,3’,5’-Tri-O-acetyl-5-methoxycarbonylmethyl-2-thiouridine

• UNSPSC Description:

  2’,3’,5’-Tri-O-acetyl-5-methoxycarbonylmethyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Oligonucleotides

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/2-3-5-tri-o-acetyl-5-methoxycarbonylmethyl-2-thiouridine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(O[C@H]1[C@@H](OC(C)=O)[C@H](N2C(NC(C(CC(OC)=O)=C2)=O)=S)O[C@@H]1COC(C)=O)=O

• Molecular Weight:

  458.44

• References & Citations:

  [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1613530-52-1