2’,3’,5’-Tri-O-acetyl-5-(trifluoromethyl)uridine

2’,3’,5’-Tri-O-acetyl-5-(trifluoromethyl)uridine

• CAS Number: 84500-34-5
• UNSPSC Description: 2’,3’,5’-Tri-O-acetyl-5-(trifluoromethyl)uridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/2-3-5-tri-o-acetyl-5-trifluoromethyl-uridine.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C(C(F)(F)F)=C1)NC(N1[C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H]2OC(C)=O)=O
• Molecular Weight: 438.31
• References & Citations: [1]Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported