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3’-Beta-C-Ethynyl-5-fluorouridine

CAT:
804-HY-154141
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
3’-Beta-C-Ethynyl-5-fluorouridine - image 1

3’-Beta-C-Ethynyl-5-fluorouridine

  • UNSPSC Description: 3’-Beta-C-Ethynyl-5-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 3’-Beta-C-Ethynyl-5-fluorouridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • Target Antigen: Nucleoside Antimetabolite/Analog
  • Type: Oligonucleotides
  • Related Pathways: Cell Cycle/DNA Damage
  • Applications: Cancer-programmed cell death
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/3-beta-c-ethynyl-5-fluorouridine.html
  • Solubility: 10 mM in DMSO
  • Smiles: O[C@@H]1[C@](O)(C#C)[C@@H](CO)O[C@H]1N(C(N2)=O)C=C(F)C2=O
  • Molecular Weight: 286.21
  • References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
  • Shipping Conditions: Room temperature
  • Clinical Information: No Development Reported