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5'-Deoxy-5‘-iodothymidine

CAT: 0804-HY-154347Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-154347Size:1 Each
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Description
5′-Deoxy-5′-iodothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
CAS Number
25953-14-4
UNSPSC
12352005
Target
Apoptosis
Type
Oligonucleotides
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-deoxy-5-iodothymidine.html
Solubility
10 mM in DMSO
Smiles
O=C(C(C)=C1)NC(N1[C@@H]2O[C@H](CI)[C@@H](O)C2)=O
Molecular Formula
C10H13IN2O4
Molecular Weight
352.13
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

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