SB-649701

• Description:

  SB-649701 is a potent human CCR8 antagonist, with a pIC50 of 7.7. AZ084 can be used for the research of asthma[1].

• UNSPSC:

  12352005

• Target:

  CCR

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/sb-649701.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=CC2=C(C=C1)N=CC=C2[C@@H]3CN(C4CCN(CC4)CC5=CC6=CC=CC=C6N5)C(O3)=O

• Molecular Formula:

  C27H28N4O3

• Molecular Weight:

  456.54

• References & Citations:

  [1]Jin J, et, al. Oxazolidinones as novel human CCR8 antagonists. Bioorg Med Chem Lett. 2007 Mar 15;17 (6) :1722-5.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  CCR8

• CAS Number:

  [935262-95-6]