Tyrosine-PEG4-aminooxy-MMAF

• UNSPSC Description:

  Tyrosine-PEG4-aminooxy-MMAF is a Linker-Payload conjugate that can be used to synthesize ARX788[1].

• Target Antigen:

  Drug-Linker Conjugates for ADC

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/tyrosine-peg4-aminooxy-mmaf.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC([C@H](CC1=CC=CC=C1)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)CCOCCOCCOCCO/N=C(C)/C3=CC=C(C[C@H](C(O)=O)N)C=C3)=O)=O)=O)OC)=O)=O

• Molecular Weight:

  1112.40

• References & Citations:

  [1]Sheo B Singh, et al. Discovery and Development of Dolastatin 10-Derived Antibody Drug Conjugate Anticancer Drugs. J Nat Prod. 2022 Mar 25;85(3):666-687.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported