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PEG4-aminooxy-MMAF

CAT: 0931-T18534-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T18534-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1415246-35-3
Target
Drug-Linker Conjugates for ADC, Microtubule Associated
Related Pathways
Cytoskeletal Signaling, Antibody-drug Conjugate/ADC Related
Bioactivity
PEG4-aminooxy-MMAF is a drug-linker conjugate designed for antibody-drug conjugates (ADC) that exhibits potent antitumor activity. It incorporates MMAF, a powerful antitubulin agent, connected through a non-cleavable PEG4 linker[1].
Smiles
[H][C@]1(CCCN1C(=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)CCOCCOCCOCCON)C(C)C)[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Molecular Formula
C47H82N6O12
Molecular Weight
923.19
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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