Aminooxy-PEG4-alcohol

• UNSPSC Description:

  Aminooxy-PEG4-alcohol is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-PEG4-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].

• Target Antigen:

  ADC Linker; PROTAC Linkers

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/aminooxy-peg4-alcohol.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NOCCOCCOCCOCCO

• Molecular Weight:

  209.24

• References & Citations:

  [1]Heather D. Maynard, et al. Method of creating hydrogels through oxime bond formation. US20150202305A1.|[2]Murray BS, et al. Reactive thermoresponsive copolymer scaffolds. Chem Commun (Camb). 2010 Dec 7;46(45):8651-3.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  106492-60-8