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Leukotriene C4

CAT: 0804-HY-113446Size: 25 μg (159.8 μM x 250 μL in Ethanol)Dry Ice: NoHazardous: No
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CAT#:0804-HY-113446Size:25 μg (159.8 μM x 250 μL in Ethanol)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Leukotriene C4 is a eicosanoid lipid mediator and produced by immune cells during type 2 inflammation. Leukotriene C4 can mediate inflammation, allergy, bronchoconstriction, and vascular leakage[1][2].
CAS Number
72025-60-6
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/leukotriene-c4.html
Concentration
159.8 μM * 250 μL in Ethanol
Purity
97.0
Solubility
10 mM in DMSO
Smiles
OC(CCC[C@H](O)[C@@H](/C=C/C=C/C=C\C/C=C\CCCCC)SC[C@@H](C(NCC(O)=O)=O)NC(CC[C@H](N)C(O)=O)=O)=O
Molecular Formula
C30H47N3O9S
Molecular Weight
625.77
Precautions
H302, H315, H319, H335
References & Citations
[1]Voisin T, et, al. The CysLT2R receptor mediates leukotriene C4-driven acute and chronic itch. Proc Natl Acad Sci U S A. 2021 Mar 30;118 (13) :e2022087118. |[2]Dvash E, et, al. Leukotriene C4 is the major trigger of stress-induced oxidative DNA damage. Nat Commun. 2015 Dec 11;6:10112.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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