Gal-C4-Chol

• Description :

  Gal-C4-Chol is a glycosylated cholesterol derivative. Gal-C4-Chol can be used as a ligand for asialoglycoprotein receptors (ASGPR) to prepare Galactosylated (Gal) liposomes. Gal-C4-Chol can be used to prepare simple lipid-based nanoparticles[1][2][3].

• UNSPSC :

  12352200

• Target :

  Liposome

• Type :

  Biochemical Assay Reagents

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/gal-c4-chol.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)OC(NCCCCNC(CS[C@@H]4O[C@@H]([C@@H]([C@@H]([C@H]4O)O)O)CO)=N)=O)([H])[C@@]5([H])[C@](CC3)([C@@](CC5)([H])[C@H](C)CCCC(C)C)C

• Molecular Formula :

  C40H69N3O7S

• Molecular Weight :

  736.06

• References & Citations :

  [1]Miller AD. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10 (6) :781-811. |[2]Managit C, et al. Effect of galactose density on asialoglycoprotein receptor-mediated uptake of galactosylated liposomes. J Pharm Sci. 2005 Oct;94 (10) :2266-75.|[3]Kawakami S, et al. Biodistribution characteristics of mannosylated, fucosylated, and galactosylated liposomes in mice. Biochim Biophys Acta. 2000 Dec 15;1524 (2-3) :258-65.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Biochemical Assay Reagents

• Clinical Information :

  No Development Reported

• CAS Number :

  [219850-70-1]