ATU027 (sodium)

• Description:

  ATU027 sodium is a siRNA, which silences expression of protein kinase N3 (PKN3) in the vascular endothelium. ATU027 sodium has previously been shown to inhibit local tumor invasion as well as lymph node and pulmonary metastasis in mouse cancer models.

• UNSPSC:

  12352208

• Target:

  Small Interfering RNA (siRNA)

• Type:

  Oligonucleotides

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/atu027-sodium.html

• Purity:

  99.22

• Solubility:

  10 mM in H2O

• Smiles:

  [ATU027 (sodium) ]

• References & Citations:

  [1]Aleku M, Schulz P, Keil O, et al. Atu027, a liposomal small interfering RNA formulation targeting protein kinase N3, inhibits cancer progression. Cancer Res. 2008;68 (23) :9788-9798. doi:10.1158/0008-5472.CAN-08-2428

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Oligonucleotides

• Clinical Information:

  Phase 2