ATU027

CAT: 0804-HY-153482-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-153482-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

ATU027 is a siRNA, which silences expression of protein kinase N3 (PKN3) in the vascular endothelium. ATU027 has previously been shown to inhibit local tumor invasion as well as lymph node and pulmonary metastasis in mouse cancer models.

CAS Number

1415935-22-6

UNSPSC

12352208

Target

Small Interfering RNA (siRNA)

Type

Oligonucleotides

Related Pathways

Epigenetics

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/atu027.html

Purity

99.22

Solubility

10 mM in H2O

Smiles

[3H][*][U][U][U][U][U][U][U][U][U][U][U][U][U][U][U][U][U][U][U][U][U][U][U][U][U][U][U]

References & Citations

[1]Aleku M, Schulz P, Keil O, et al. Atu027, a liposomal small interfering RNA formulation targeting protein kinase N3, inhibits cancer progression. Cancer Res. 2008;68 (23) :9788-9798. doi:10.1158/0008-5472.CAN-08-2428

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Oligonucleotides

Clinical Information

Phase 2

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ATU027

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