DM-CO-(CH2)5-SMe

DM-CO-(CH2)5-SMe

• CAS Number: 2243689-84-9
• UNSPSC Description: DM-CO-(CH2)5-SMe is an anticancer agent derived from antibody-drug conjugates (ADC) metabolite with cytotoxicity to H1703, H1975, COLO704 and Colo720E cells[1].
• Target Antigen: Drug Metabolite
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/dm-co-ch2-5-sme.html
• Solubility: 10 mM in DMSO
• Smiles: C[C@]12[C@@]([C@@H]([C@]3([H])C[C@]([C@@H](/C=C/C=C(CC4=CC(N(C(C[C@@H]2OC([C@H](C)N(C)C(CCCCCSC)=O)=O)=O)C)=C(C(OC)=C4)Cl)\C)OC)(NC(O3)=O)O)C)([H])O1
• Molecular Weight: 794.39
• References & Citations: [1]Widdison, et al. Preparation of maytansinoid derivatives with self-immolative peptide linkers and their conjugates as antitumor agents. World Intellectual Property Organization. WO2018160539.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported