2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine

2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine

• CAS Number: 176755-86-5
• UNSPSC Description: 2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/2-deoxy-5-o-dmt-n4-fmoc-5-methylcytidine.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]1C[C@H](COC(C2=CC=C(OC)C=C2)(C3=CC=C(OC)C=C3)C4=CC=CC=C4)O[C@H]1N5C=C(C)C(NC(OCC6C7=C(C=CC=C7)C8=C6C=CC=C8)=O)=NC5=O
• Molecular Weight: 765.85
• References & Citations: [1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported