2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine

• UNSPSC Description:

  2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Oligonucleotides

• Related Pathways:

  Cell Cycle/DNA Damage

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/2-deoxy-5-o-dmt-n4-fmoc-5-methylcytidine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@H]1C[C@H](COC(C2=CC=C(OC)C=C2)(C3=CC=C(OC)C=C3)C4=CC=CC=C4)O[C@H]1N5C=C(C)C(NC(OCC6C7=C(C=CC=C7)C8=C6C=CC=C8)=O)=NC5=O

• Molecular Weight:

  765.85

• References & Citations:

  [1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  176755-86-5