2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine 3'-CE-phosphoramidite

CAT:

804-HY-152979

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CAS Number: 176755-87-6
UNSPSC Description: 2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine 3'-CE-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
Target Antigen: DNA/RNA Synthesis
Type: Oligonucleotides
Related Pathways: Cell Cycle/DNA Damage
Field of Research: Others
Assay Protocol: https://www.medchemexpress.com/2-deoxy-5-o-dmt-n4-fmoc-5-methylcytidine-3-ce-phosphoramidite.html
Solubility: 10 mM in DMSO
Smiles: O=C1N=C(NC(OCC2C3=C(C=CC=C3)C4=C2C=CC=C4)=O)C(C)=CN1[C@H]5C[C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](COC(C6=CC=CC=C6)(C7=CC=C(OC)C=C7)C8=CC=C(OC)C=C8)O5
Molecular Weight: 966.07
References & Citations: [1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-152979	2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine 3'-CE-phosphoramidite
HY-152978	2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine
HY-152983	2'-Deoxy-5'-O-DMT-N6-Fmoc-adenosine 3'CE-phosphoramidite
HY-104039	2'-Deoxy-5'-O-DMT-5-methylcytidine
HY-154019	N4-Benzoyl-5'-O-DMT-5-methylcytidine
HY-154450	N4-Benzoyl-5’-O-DMT-3’-O-(2-methoxyethyl)-5-methylcytidine
HY-48873	5'-O-DMT-5-Ethynyl-2'-deoxyuridine 3'-CE phosphoramidite
HY-W392836	2'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite
HY-W087199	N6-Benzoyl-2'-deoxy-5'-O-DMT-a-adenosine 3'-CE phosphoramidite
HY-154441	N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine

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