2'-Deoxy-5'-O-DMT-5-methylcytidine

2'-Deoxy-5'-O-DMT-5-methylcytidine

• CAS Number: 176755-83-2
• UNSPSC Description: 2'-Deoxy-5'-O-DMT-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/2-deoxy-5-o-dmt-5-methylcytidine.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]1C[C@H](N2C(N=C(N)C(C)=C2)=O)O[C@@H]1COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5
• Molecular Weight: 543.61
• References & Citations: [1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported