N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine

• UNSPSC Description:

  N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Oligonucleotides

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/n4-benzoyl-3-o-dmt-2-o-2-methoxyethyl-5-methylcytidine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1N=C(NC(C2=CC=CC=C2)=O)C(C)=CN1[C@@H]3O[C@@H]([C@H]([C@H]3OCCOC)OC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)CO

• Molecular Weight:

  721.79

• References & Citations:

  [1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported