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Mp-dLAE-PABC-MMAE

CAT: 0804-HY-152916-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-152916-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mp-dLAE-PABC-MMAE is a agent-linker conjugate for ADC. mp-dLAE-PABC-MMAE contains a potent tubulin inhibitor Monomethyl auristatin E. mp-dLAE-PABC-MMAE can be used to synthesis antibody-drug conjugates (ADCs).
CAS Number
2625616-44-4
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mp-dlae-pabc-mmae.html
Purity
98.31
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N([C@H]([C@@H](CC(N1[C@H]([C@H](OC)[C@H](C(N[C@@H]([C@@H](O)C2=CC=CC=C2)C)=O)C)CCC1)=O)OC)[C@@H](C)CC)C)=O)=O)OCC3=CC=C(NC([C@H](CCC(O)=O)NC([C@H](C)NC([C@@H](CC(C)C)NC(CCN4C(C=CC4=O)=O)=O)=O)=O)=O)C=C3
Molecular Formula
C68H102N10O17
Molecular Weight
1331.59
References & Citations
[1]Sandall Sharsti and Waight Andrew. Engineering of anti-CD228 antibodies and antibody-drug conjugates for cancer immunotherapy. WO2022031652. 2022.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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