Ac-Lys-Val-Cit-PABC-MMAE

Ac-Lys-Val-Cit-PABC-MMAE

• CAS Number: 1650569-89-3
• UNSPSC Description: Ac-Lys-Val-Cit-PABC-MMAE is a agent-linker conjugate for ADC. Ac-Lys-Val-Cit-PABC-MMAE contains the ADC linker (peptide Ac-Lys-Val-Cit-PABC) and a potent tubulin polymerization inhibitor MMAE (HY-15162)[1].
• Target Antigen: Drug-Linker Conjugates for ADC
• Type: ADC Related
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/ac-lys-val-cit-pabc-mmae.html
• Solubility: DMSO : ≥ 200 mg/mL
• Smiles: O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@@H](NC(C)=O)CCCCN)=O)=O)=O)=O)=O)=O)=O)OC)=O
• Molecular Weight: 1293.64
• References & Citations: [1]Kleniman, et al. Engineered polypeptide conjugates. WO2015015448A2.
• Shipping Conditions: Blue Ice
• Clinical Information: No Development Reported