5-Methoxy-4’-thiouridine

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804-HY-152821

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UNSPSC Description: 5-Methoxy-4’-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen: Nucleoside Antimetabolite/Analog
Type: Oligonucleotides
Related Pathways: Cell Cycle/DNA Damage
Applications: Cancer-programmed cell death
Field of Research: Others
Assay Protocol: https://www.medchemexpress.com/5-methoxy-4-thiouridine-a.html
Solubility: 10 mM in DMSO
Smiles: O[C@H]1[C@@H](O)[C@H](N(C(N2)=O)C=C(OC)C2=O)S[C@@H]1CO
Molecular Weight: 290.29
References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-152540	5-Methoxy-4-thiouridine
HY-152821	5-Methoxy-4’-thiouridine
HY-152700	5-Methoxy-2-thiouridine
HY-152698	5-Methyl-4’-thiouridine
HY-152533	5-Ethyl-4-thiouridine
HY-152505	5-Methyl-4-thiouridine
HY-152298	5-Fluoro-4’-thiouridine
HY-154840-03	4-Thiouridine 5′-triphosphate (tetralithium)
HY-154840-04	4-Thiouridine 5′-triphosphate (tetralithium)
HY-154840-02	4-Thiouridine 5′-triphosphate (tetralithium)