4-Thiouridine

• Description :

  4-Thiouridine is a ribonucleoside analog, it is widely used in RNA analysis and (m) RNA labeling. 4-Thiouridine inhibits rRNA synthesis and causes a nucleolar stress response[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Nucleoside Antimetabolite/Analog

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/4-thiouridine-a.html

• Purity :

  99.68

• Solubility :

  DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

• Smiles :

  O=C(N1)N([C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2)C=CC1=S

• Molecular Formula :

  C9H12N2O5S

• Molecular Weight :

  260.27

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Burger K, et al. 4-thiouridine inhibits rRNA synthesis and causes a nucleolar stress response. RNA Biol. 2013 Oct;10 (10) :1623-30.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [13957-31-8]