5-Methoxy-2-thiouridine

CAT: 0804-HY-152700Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-152700Size:1 Each
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Description
5-Methoxy-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
CAS Number
[30771-43-8]
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/5-methoxy-2-thiouridine.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@@H](O)[C@H](N(C(N2)=S)C=C(OC)C2=O)O[C@@H]1CO
Molecular Formula
C10H14N2O6S
Molecular Weight
290.29
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

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