5-Methoxy-4-thiouridine

• Description:

  5-Methoxy-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

• UNSPSC:

  12352005

• Target:

  Nucleoside Antimetabolite/Analog

• Type:

  Oligonucleotides

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/5-methoxy-4-thiouridine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(NC(C(OC)=C2)=S)=O)O1

• Molecular Formula:

  C10H14N2O6S

• Molecular Weight:

  290.29

• References & Citations:

  [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Oligonucleotides

• Clinical Information:

  No Development Reported

• CAS Number:

  [37805-89-3]