Antibacterial agent 130

• Description :

  Antibacterial agent 130 is a 1,1-diarylthiogalactoside, used for targeting the Pseudomonas aeruginosa LecA. Antibacterial agent 130 shows high affinity toward LecA (Kd=1 μM) . Antibacterial agent 130 has antibiofilm activity, but lacks bactericidal activity. LecA, a lectin and virulence factor from Pseudomonas aeruginosa involved in bacterial adhesion and biofilm formation[1].

• UNSPSC :

  12352005

• Target :

  Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/antibacterial-agent-130.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OC[C@H]1O[C@@H](SC2=C(OC)C=CC(C(C3=CC(OC)=C(OC)C(OC)=C3)=O)=C2)[C@H](O)[C@@H](O)[C@H]1O

• Molecular Formula :

  C23H28O10S

• Molecular Weight :

  496.53

• References & Citations :

  [1]Bruneau A, et al. Discovery of potent 1,1-diarylthiogalactoside glycomimetic inhibitors of Pseudomonas aeruginosa LecA with antibiofilm properties. Eur J Med Chem. 2022 Dec 15;247:115025.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1502721-60-9]