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Thrombin inhibitor 7

CAT: 0804-HY-152150Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-152150Size:1 Each
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Description
Thrombin inhibitor 7 is a potent FXIIa inhibitor with IC50 values of 28 nM, >132 µM for FXIIa and FXIa, respectively. Thrombin inhibitor 7 shows low cytotoxicity[1].
CAS Number
2866508-00-9
UNSPSC
12352005
Target
Ser/Thr Protease
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/thrombin-inhibitor-7.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C2=NN(C(C3=CC=CC4=C3C=CC=C4)=O)C(N)=N2)N=C5C=CC=CC5=N1)NCCCC
Molecular Formula
C26H23N7O2
Molecular Weight
465.51
References & Citations
[1]Imberg L, et al. Amide-functionalized 1,2,4-Triazol-5-amines as Covalent Inhibitors of Blood Coagulation Factor XIIa and Thrombin. ACS Pharmacol Transl Sci. 2022 Nov 30;5 (12) :1318-1347.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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