Thrombin inhibitor 1

• UNSPSC Description:

  Thrombin inhibitor 1 is a potent thrombin inhibitor (Ki=0.66 nM, 2xaPTT=0.43 μM).

• Target Antigen:

  Thrombin

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/2-Pyridineacetamide,_3-chloro-N-[_1R_-1-_3-chlorophenyl_ethyl]-6-[[2,2-difluoro-2-_1-oxido-2-pyridinyl_ethyl]amino]-,_1-oxide.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@H](C1=CC(Cl)=CC=C1)NC(CC2=C(Cl)C=CC(NCC(F)(C3=CC=CC=N3=O)F)=N2=O)=O

• Molecular Weight:

  497.32

• References & Citations:

  [1]Nantermet PG, et al. P2 pyridine N-oxide thrombin inhibitors: a novel peptidomimetic scaffold. Bioorg Med Chem Lett. 2005 Jun 2;15(11):2771-5.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  855998-46-8