SARS-CoV-2/MERS Mpro-IN-2

SARS-CoV-2/MERS Mpro-IN-2

• UNSPSC Description: SARS-CoV-2/MERS Mpro-IN-2 (compound 9d) is a potent SARS-CoV-2 and MERS main protease inhibitor with IC50 values of 0.21, 0.07 µM, respectively[1].
• Target Antigen: SARS-CoV
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/sars-cov-2-mers-mpro-in-2.html
• Solubility: 10 mM in DMSO
• Smiles: O=C([C@H]1N(C(COC2=CC=C(Cl)C=C2Cl)=O)CCC1)N[C@H](C(C(NCC3=CC=CC=C3)=O)=O)C[C@H]4C(NCC4)=O
• Molecular Weight: 589.47
• References & Citations: [1]Pelliccia S, et al. Easy access to α-ketoamides as SARS-CoV-2 and MERS Mpro inhibitors via the PADAM oxidation route. Eur J Med Chem. 2022 Dec 15;244:114853.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported