SARS-CoV-2/MERS Mpro-IN-1

• UNSPSC Description:

  SARS-CoV-2/MERS Mpro-IN-1 (compound 9c) is a potent SARS-CoV-2 and MERS main protease inhibitor with IC50 values of 0.10, 0.06 µM, respectively[1].

• Target Antigen:

  SARS-CoV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/sars-cov-2-mers-mpro-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N1[C@H](C(N[C@H](C(C(NCCC2=CC=CC=C2OC)=O)=O)C[C@H]3C(NCC3)=O)=O)CCC1)OCC4=CC=CC=C4

• Molecular Weight:

  564.63

• References & Citations:

  [1]Pelliccia S, et al. Easy access to α-ketoamides as SARS-CoV-2 and MERS Mpro inhibitors via the PADAM oxidation route. Eur J Med Chem. 2022 Dec 15;244:114853.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported