SARS-CoV-2/MERS Mpro-IN-1

SARS-CoV-2/MERS Mpro-IN-1

• UNSPSC Description: SARS-CoV-2/MERS Mpro-IN-1 (compound 9c) is a potent SARS-CoV-2 and MERS main protease inhibitor with IC50 values of 0.10, 0.06 µM, respectively[1].
• Target Antigen: SARS-CoV
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/sars-cov-2-mers-mpro-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N1[C@H](C(N[C@H](C(C(NCCC2=CC=CC=C2OC)=O)=O)C[C@H]3C(NCC3)=O)=O)CCC1)OCC4=CC=CC=C4
• Molecular Weight: 564.63
• References & Citations: [1]Pelliccia S, et al. Easy access to α-ketoamides as SARS-CoV-2 and MERS Mpro inhibitors via the PADAM oxidation route. Eur J Med Chem. 2022 Dec 15;244:114853.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported