SARS-CoV-2 Mpro-IN-6

SARS-CoV-2 Mpro-IN-6

• CAS Number: 2768834-48-4
• UNSPSC Description: SARS-CoV-2 Mpro-IN-6 is a covalent, irreversible and selective SARS-CoV-2 Mpro inhibitor with an IC50 of 0.18 μM. SARS-CoV-2 Mpro-IN-6 does not inhibit human cathepsins B, F, K, and L, and caspase 3[1].
• Target Antigen: SARS-CoV
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/sars-cov-2-mpro-in-6.html
• Solubility: 10 mM in DMSO
• Smiles: O=C([C@H]1N(C2=CC=C(Cl)C(Cl)=C2)CCN(C(CCl)=O)C1)NCC3=CC=CS3
• Molecular Weight: 446.78
• References & Citations: [1]Shenghua Gao, et al. Discovery and Crystallographic Studies of Nonpeptidic Piperazine Derivatives as Covalent SARS-CoV-2 Main Protease Inhibitors. J Med Chem. 2022 Dec 22;65(24):16902-16917.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported