SARS-CoV MPro-IN-1

• UNSPSC Description:

  SARS-CoV MPro-IN-1 is a SARS-CoV-2 3CLpro covalent inhibitor, with an IC50 of 40 nM. SARS-CoV MPro-IN-1 shows good anti-SARS-CoV-2-infection activity in cell culture with an EC50 of 0.33 μM. SARS-CoV MPro-IN-1 has the potential for COVID-19 research[1].

• Target Antigen:

  SARS-CoV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/sars-cov-mpro-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC2=CC=CC=C2N1)N[C@H](C(N[C@H](C=O)C[C@H](CCN3)C3=O)=O)CC4=CC(F)=CC=C4

• Molecular Weight:

  464.49

• References & Citations:

  [1]Dai W, et al. Structure-Based Design, Synthesis and Biological Evaluation of Peptidomimetic Aldehydes as a Novel Series of Antiviral Drug Candidates Targeting the SARS-CoV-2 Main Protease. bioRxiv; 2020.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2413716-71-7