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6-Azidohexanoyl-Val-Cit-PAB

CAT: 0804-HY-151700-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-151700-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
6-Azidohexanoyl-Val-Cit-PAB is a click chemistry reagent that can be used to synthesis vaccine[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
CAS Number
1613321-02-0
UNSPSC
12352005
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/6-azidohexanoyl-val-cit-pab.html
Solubility
10 mM in DMSO
Smiles
O=[N+]([O-])C(C=C1)=CC=C1OC(OCC(C=C2)=CC=C2NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN=[N+]=[N-])=O)=O)=O)=O
Molecular Formula
C31H41N9O9
Molecular Weight
683.71
References & Citations
[1]Anderson RJ, Painter GF, et al. NKT cell-dependent glycolipid-peptide vaccines with potent anti-tumour activity. Chem Sci. 2015 Sep 1;6 (9) :5120-5127.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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