Products for Research Use Only
RegisterLogin

Val-Cit-PAB-OSBT

CAT: 0804-HY-78736-01Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-78736-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Val-Cit-PAB-OSBT is a degradable ADC linker, which is composed of the polypeptide Val-Cit-PAB and OSBT groups coupled together[1].
CAS Number
2210262-26-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/val-cit-pab-osbt.html
Purity
99.77
Solubility
DMSO : 300 mg/mL (ultrasonic)
Smiles
N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(CO[Si](C)(C)C(C)(C)C)C=C1)=O)=O
Molecular Formula
C24H43N5O4Si
Molecular Weight
493.71
Precautions
H302, H315, H319, H335
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

Val-Cit-PAB-OSBT
CAS Number2210262-26-1
PubChem CID118703635
IUPAC Name(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-N-[4-[[tert-butyl(dimethyl)silyl]oxymethyl]phenyl]-5-(carbamoylamino)pentanamide
Molecular FormulaC24H43N5O4Si
Molecular Weight493.7
Topological Polar Surface Area149
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count5
Rotatable Bond Count13
Heavy Atom Count34
Formal Charge0
Complexity673
SMILES
CC(C)[C@@H](C(=O)N[C@@H](CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)CO[Si](C)(C)C(C)(C)C)N
InChI
InChI=1S/C24H43N5O4Si/c1-16(2)20(25)22(31)29-19(9-8-14-27-23(26)32)21(30)28-18-12-10-17(11-13-18)15-33-34(6,7)24(3,4)5/h10-13,16,19-20H,8-9,14-15,25H2,1-7H3,(H,28,30)(H,29,31)(H3,26,27,32)/t19-,20-/m0/s1
InChIKey
GFLUZYWIOXHYRH-PMACEKPBSA-N
Chemical Structure
2D Structure
2D structure of Val-Cit-PAB-OSBT
CAS: 2210262-26-1
CID: 118703635
Formula: C24H43N5O4Si
MW: 493.7
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight493.7
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count5
Rotatable Bond Count13
Exact Mass493.30843140
Monoisotopic Mass493.30843140
Topological Polar Surface Area149 Ų
Heavy Atom Count34
Formal Charge0
Complexity673
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-126667SC-Val-Cit-PAB
HY-153031-01Val-Cit-PAB-Exatecan
HY-19318-01Fmoc-Val-Cit-PAB
HY-141141-01Boc-Val-Cit-PAB
HY-100374-01Val-Cit-PAB-MMAE
HY-12362-01Val-cit-PAB-OH
HY-78738-01MC-Val-Cit-PAB
HY-101909Val-Cit-PAB-MMAF
HY-140014-01Val-Cit
HY-44177-01Val-Cit-PAB-MMAF (sodium)

Alternative Products

CatalogName
T84832-01Val-Cit-PAB-OSBT
OR471212-01Val-Cit-PAB
M19787-01MC-Val-Cit-PAB
BA2692-1Val-Cit-PAB-Exatecan
BA2625-50Val-Cit-PAB-MMAE
BA2482-1000Boc-Val-Cit-PAB
FV145679-01Val-Cit-PAB-OH
FF176695-01Fmoc-val-cit-pab
C56014-500MGFmoc-​Val-​Cit-​PAB
MBS5822538Val-Cit-PAB-MMAF

Popular Products