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CAII-IN-2

CAT: 0804-HY-151494Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-151494Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CAII-IN-2 (compound 3g), a thiosemicarbazide derivative, is a potent, selective carbonic anhydrase-II (CA-II) inhibitor with an IC50 value of 12.1 μM for bovine CA-II. CAII-IN-2 can be used in research of carbonic anhydrase related biological disorders[1].
UNSPSC
12352005
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/caii-in-2.html
Solubility
10 mM in DMSO
Smiles
CN(C1=CC=C(C=C1)/C=C/C=N/NC(NC2=CC=C(C=C2)Br)=S)C
Molecular Formula
C18H19BrN4S
Molecular Weight
403.34
References & Citations
[1]Rasool A, et, al. Bis-pharmacophore of cinnamaldehyde-clubbed thiosemicarbazones as potent carbonic anhydrase-II inhibitors. Sci Rep. 2022 Sep 27;12 (1) :16095.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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C1105-12ACarbonic Anhydrase II (CAII)
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