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Anticancer agent 83

CAT: 0804-HY-151426Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-151426Size:1 Each
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Description
Anticancer agent 83 is a potent anticancer agent, inhibits LOX IMVI cells growth with a GI50 value of 0.15 mM. Anticancer agent 83 reduces mitochondrial membrane potential and induces DNA damage to induces leukemia cells apoptosis[1].
CAS Number
[904815-29-8]
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-83.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C)N(C2=CC=C(C(C)C)C=C2)N=N1)NC3=CC=C(SC#N)C=C3
Molecular Formula
C20H19N5OS
Molecular Weight
377.46
References & Citations
[1]Pokhodylo N, et al. Novel N- (4-thiocyanatophenyl) -1H-1,2,3-triazole-4-carboxamides exhibit selective cytotoxic activity at nanomolar doses towards human leukemic T-cells. Eur J Med Chem. 2022 Nov 5;241:114633.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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